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Analytical Chemistry for drug discovery

Our analytical chemistry, purification, and separation research groups are able to offer high-quality analytical services.

Thanks to our extensive experience in the chemical and pharmaceutical fields and state-of-the-art instrumentation, we offer a broad portfolio of analytical chemistry services, from early discovery to final product release, using advanced methods.

Solutions for R&D, analytical development and quality control testing

Our academic researchers have wide experience in chemical analysis, and our laboratories are equipped with state-of-the-art analytical instrumentation for spectroscopic and spectrometric determinations.

We can provide effective and efficient solutions for R&D, analytical development and quality control testing, helping to expedite your drug discovery programs.

Among our researchers, we can boast recognized experience in the separation, characterization, and purification of active organic compounds contained in natural products, with unique analytical research experience in the nutraceutical and food science field, to provide effective and efficient solutions analytical development and quality control testing.

Furthermore, our analytical chemistry for drug discovery services pay close attention to the deep understanding of environmental science, helping our collaborators to undertake the most effective and cost-efficient strategy.

Our services

DSF’s Analytical Chemistry for drug discovery services includes:

  1. LC-MS analysis
  2. Preparation and separation in preparative HPLC
  3. Elemental analysis and atomic absorption spectroscopy
  4. Development and validation of immunoassays
  5. Separating and monitoring impurities in starting materials, intermediates, APIs, and final products HPLC
  6. Complete data – including 1D/2D NMR, LCMS, EA, HRMS, IR and UV – to identify the structure of the separated impurities
  7. Collecting, Isolating and identifying the structures of API degradation products by forced oxidation
  8. Employment of QNMR to quickly determine the contents of crude materials, intermediates, API and synthetic impurities
  9. NMR 1D, 2D, etc. (including H-NMR, C-NMR, P-NMR, F-NMR, HSQC, HMBC, COSY and NOESY), LC-MS analysis
  10. Chiral purity test
  11. Preparation and separation in preparative HPLC
  12. Routine physical and chemical tests (ROI, LOD, Cl-, SO42-, mp, HM, optical rotation, moisture determination, heavy metal residues, etc.)
  13. Analytical evaluation of small molecule-biopolymers interactions

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